Immuno-Phormocology Lab
Register No. 11016
Discipline : Marine Biotechnology
Date of Viva Voce : 09 – 05 – 2025
Dr. ASHA . S, inspire fellow worked on the Cloning and expression of halophilic DNase from marine bacteria. She screened marine sediment bacteria offcoast Kanyakumari for DNase production and selected four strains with prominent enzyme production. One among them, Bacillus pacificus was found to be promising and the their whole genome was elucidated to identify the genes responsible for DNase production. The gene, identified as Nuc A was cloned and expressed. The expresssed DNase was found to have application in cancer therapeutics and wound healing.
Register No. 19117042102003
Discipline : Microbiology
Date of Viva Voce : 16-09-2025
Ms. RATHIKA . R is pious in Development of Autophagy Modulators from Azole Derivatives as Therapeutics for Colorectal Cancer. She was involved in synthesis of Azole derivatives based on a natural product template from marine bacteria. The derivatives were screened in silico for their ability to modulate autophagy targets like mTOR, AKT and PI3K. The best among the derivatives were examined in vitro for their ability to destroy cancer cells and their mechanism of inducing autophagic or apoptotic cell death was elucidated. She came up with two azole derivatives with therapeutic potential on colon carcinoma.
Register No. 12508
Discipline : Zoology
Date of Viva Voce : 14-11- 2025
Mr. BIJU . Y explored the Status of native Artemia population in the saltpans of Kanyakumari district due to the spread of exotic species. The complete eradication of native strain Artemia parthenogenetica was observed in his study. The biology of exotic A. franciscana contributes to the dispersal of artemia cysts and replacement of native artemia in the study area. The fecudunity rate, attainment of sexual maturity in short span, adaptation to critically hypersaline have favoured not only the reproduction and survival of this invasive strain but also their dominance deprived the existence of native strain. Also migratory and shorebirds of this area have contributed for their survival efficiency.
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